Polynucleotides: A Deep Dive into Skin Rejuvenation
- Nimesh Dave
- Oct 19, 2024
- 2 min read

In the ever-evolving world of aesthetic medicine, polynucleotides are increasingly gaining popularity and attention, with social media showcasing these molecules as taking the skincare industry by storm in recent months. But what exactly are polynucleotides, and how do they contribute to aesthetics?
Let's delve into the science behind these powerful agents and their transformative uses in skin care.
Polynucleotides are long chains of nucleotides, which are the basic structural units of DNA and RNA. These molecules are essential for various biological processes, including cellular repair and regeneration. In aesthetic practice, polynucleotides have been highlighted for their ability to stimulate fibroblast activity, which in turn boosts collagen and elastin production. This leads to improved skin texture, increased elasticity, and overall rejuvenation.
The use of polynucleotides in aesthetic treatments is multifaceted. They have been shown to improve skin texture, reduce wrinkle depth, and enhance facial appearance. By encouraging cell growth and turnover, polynucleotides improve elasticity, hydrate the skin, and offer anti-inflammatory properties. This makes them an effective solution for a range of concerns, including wrinkles, lines, sunken skin due to lost collagen, dryness, dark circles, rosacea, acne scarring, and hyperpigmentation.
One of the most significant advantages of polynucleotide treatments is their non-surgical nature, positioning them as a promising option for those seeking minimally invasive procedures. They represent a significant advancement in skincare technology, offering innovative solutions for skin rejuvenation and health. Their ability to stimulate cell growth, repair tissue, reduce inflammation, and enhance skin hydration makes them a valuable tool for aesthetic practitioners.
However, it's important to note that polynucleotides used in aesthetics are generally derived from fish gonads, which means they cannot be used in patients with fish allergies. This highlights the necessity for personalized treatment plans and thorough patient consultations to ensure safety and efficacy.

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